I-Ethylene oxide (EO) isetshenziswe isikhathi eside ekubulaleni amagciwane nasekuvaleni inzalo futhi iyona kuphela ebulala igesi yamakhemikhali ebonwa umhlaba njengethembekile kakhulu. Esikhathini esedlule,i-ethylene oxideyayisetshenziswa kakhulu ekubulaleni amagciwane ngezinga lemboni kanye nokuvala inzalo. Ngokuthuthukiswa kobuchwepheshe besimanje bezimboni kanye ne-automation kanye nobuchwepheshe obuhlakaniphile, ubuchwepheshe be-ethylene oxide sterilization bungasetshenziswa ngokuphepha ezikhungweni zezokwelapha ukuze kufakwe amagciwane okunembayo kumadivayisi ezokwelapha asaba ukushisa nomswakama.

Izici ze-ethylene oxide

I-Ethylene oxideiyisizukulwane sesibili sezibulala-magciwane zamakhemikhali ngemva kwe-formaldehyde. Kusengenye yezibulali magciwane ezibandayo ezingcono kakhulu futhi iyilungu elibaluleke kakhulu lobuchwepheshe obune obukhulu bokuvala inzalo emazingeni okushisa aphansi.

I-Ethylene oxide iyinhlanganisela elula ye-epoxy. Kuyigesi engenambala ekamelweni lokushisa nokucindezela. Isinda kunomoya futhi inephunga elimnandi le-ether. I-ethylene oxide iyavutha futhi iyaqhuma. Lapho umoya uqukethe u-3% kuya ku-80%i-ethylene oxide, kwakheka igesi elixubekile eliqhumayo, elivutha noma liqhume lapho livezwa amalangabi avulekile. I-concentration ye-ethylene oxide evame ukusetshenziswa yokubulala amagciwane kanye nokuvalwa inzalo ingu-400 kuya ku-800 mg/L, esebangeni lokuhlushwa elivuthayo kanye neziqhumane emoyeni, ngakho-ke kufanele isetshenziswe ngokuqapha.

I-ethylene oxide ingaxutshwa namagesi angasebenzi njengei-carbon dioxidengesilinganiso esingu-1:9 ukuze kwakheke ingxube engaqhumi, ephephe kakhudlwana ekubulaweni amagciwane nokuvala inzalo.I-Ethylene oxideingakwazi ukwenza i-polymerize, kodwa ngokuvamile i-polymerization ihamba kancane futhi ikakhulukazi ivela esimweni soketshezi. Ezingxubeni ze-ethylene oxide ne-carbon dioxide noma i-fluorinated hydrocarbons, i-polymerization kwenzeka kancane futhi ama-polymer aqinile mancane amathuba okuthi aqhume.

Isimiso se-Ethylene Oxide Sterilization

1. I-Alkylation

Indlela yokusebenza yei-ethylene oxideekubulaleni ama-microorganisms ahlukahlukene ikakhulukazi i-alkylation. Izindawo zesenzo yi-sulfhydryl (-SH), amino (-NH2), i-hydroxyl (-COOH) ne-hydroxyl (-OH) kumaprotheni nama-nucleic acid molecule. I-Ethylene oxide ingabangela la maqembu ukuthi abhekane nokusabela kwe-alkylation, okwenza la ma-macromolecules ebhayoloji angasebenzi, ngaleyo ndlela abulale ama-microorganisms.

2. Vimbela ukusebenza kwama-enzyme ezinto eziphilayo

I-Ethylene oxide ingavimbela umsebenzi wama-enzyme ahlukahlukene we-microorganisms, njenge-phosphate dehydrogenase, i-cholinesterase namanye ama-oxidase, okuvimbela ukuqedwa kwezinqubo ezijwayelekile ze-metabolic zama-microorganisms futhi kuholele ekufeni kwabo.

3. Ukubulala umphumela kuma-microorganisms

Kokubilii-ethylene oxideuketshezi kanye negesi kunemiphumela eqinile ye-microbicidal. Uma kuqhathaniswa, umphumela we-microbicidal wegesi unamandla, futhi igesi yawo ngokuvamile isetshenziswa ekubulaleni amagciwane nasekuvaleni inzalo.

I-Ethylene oxide iyi-sterilant esebenza ngempumelelo ebanzi enomphumela oqinile wokubulala nokungasebenzi emizimbeni esakazeka amagciwane, izinhlamvu zebhaktheriya, isikhunta, namagciwane. Lapho i-ethylene oxide ihlangana nama-microorganisms, kodwa ama-microorganisms aqukethe amanzi anele, ukusabela phakathi kwe-ethylene oxide nama-microorganisms kuwukusabela okujwayelekile kokuqala. Umthamo owenza ama-microorganisms akhulisiwe angasebenzi, ijika lokusabela liwumugqa oqondile kunani le-semi-logarithmic.

Ububanzi bokusetshenziswa kwe-ethylene oxide inzalo

I-Ethylene oxideayilimazi izinto eziyinzalo futhi inokungena okuqinile. Izinto eziningi ezingafanele ukuvala inzalo ngezindlela ezijwayelekile zingabulawa amagciwane futhi zibulawe amagciwane nge-ethylene oxide. Ingasetshenziselwa ukuvala inzalo kwemikhiqizo yensimbi, ama-endoscopes, ama-dialyzers kanye namadivayisi ezokwelapha alahlwayo, ukubulala amagciwane ezimbonini kanye nokuvalwa inzalo kwezindwangu ezihlukahlukene, imikhiqizo yepulasitiki, kanye nokubulala amagciwane ezindaweni eziwumqedazwe wezifo ezithathelwanayo (njengezindwangu zemicu yamakhemikhali, isikhumba, amaphepha, imibhalo, nemidwebo kawoyela).

I-ethylene oxide ayizilimazi izinto ezifakwe inzalo futhi inokungena okuqinile. Izinto eziningi ezingafanele ukuvala inzalo ngezindlela ezijwayelekile zingabulawa amagciwane futhi zibulawe amagciwane nge-ethylene oxide. Ingasetshenziselwa ukuvala inzalo kwemikhiqizo yensimbi, ama-endoscopes, ama-dialyzers kanye namadivayisi ezokwelapha alahlwayo, ukubulala amagciwane ezimbonini kanye nokuvalwa inzalo kwezindwangu ezihlukahlukene, imikhiqizo yepulasitiki, kanye nokubulala amagciwane ezindaweni eziwumqedazwe wezifo ezithathelwanayo (njengezindwangu zemicu yamakhemikhali, isikhumba, amaphepha, imibhalo, nemidwebo kawoyela).

Izinto ezithinta umphumela wokuvala inzalo wei-ethylene oxide

Umphumela wokuvala inzalo we-ethylene oxide uthintwa yizici eziningi. Ukuze kuzuzwe umphumela ongcono kakhulu wokuvala inzalo, ngokulawula ngokuphumelelayo izici ezihlukahlukene kuphela lapho ingadlala indima yayo kangcono ekubulaleni amagciwane kanye nokufeza injongo yayo yokubulala amagciwane kanye nokuvalwa inzalo. Izici eziyinhloko ezithinta umphumela wokuvala inzalo yilezi: ukugxila, izinga lokushisa, umswakama ohlobene, isikhathi sesenzo, njll.