I-ethylene oxide (EO) ibilokhu isetshenziswa ekubulaleni nasekubulaleni amagciwane isikhathi eside futhi iyona kuphela into yokubulala amagciwane egesi yamakhemikhali eqashelwa umhlaba njengethembekile kakhulu. Esikhathini esidlule,i-ethylene oxideyayisetshenziswa kakhulu ekuhlanzeni nasekubulaleni amagciwane ngezinga lezimboni. Ngokuthuthuka kobuchwepheshe besimanje bezimboni kanye nokwenza izinto ngokuzenzakalela kanye nobuchwepheshe obuhlakaniphile, ubuchwepheshe bokubulala amagciwane be-ethylene oxide bungasetshenziswa ngokuphephile ezikhungweni zezokwelapha ukuze kuhlanzwe amadivayisi ezokwelapha anembile esaba ukushisa kanye nomswakama.

Izici ze-ethylene oxide

I-ethylene oxideiyisizukulwane sesibili sezibulala-magciwane zamakhemikhali ngemuva kwe-formaldehyde. Isesengenye yezibulala-magciwane ezibandayo ezinhle kakhulu futhi iyilungu elibaluleke kakhulu lobuchwepheshe obune obukhulu bokubulala inzalo obusezingeni eliphansi lokushisa.

I-ethylene oxide iyinhlanganisela elula ye-epoxy. Iyigesi engenambala ekamelweni lokushisa kanye nengcindezi. Inzima kunomoya futhi inephunga elimnandi le-ether. I-ethylene oxide iyavutha futhi iyaqhuma. Uma umoya uqukethe u-3% kuya ku-80%i-ethylene oxide, kwakheka igesi exubile eqhumayo, esha noma iqhume uma ivezwa emalangabini avulekile. Isilinganiso se-ethylene oxide esivame ukusetshenziswa ekubulaleni nasekubulaleni amagciwane singama-400 kuya ku-800 mg/L, esisesigabeni sokuhlushwa okuvuthayo nokuqhuma emoyeni, ngakho-ke kufanele sisetshenziswe ngokuqapha.

I-ethylene oxide ingaxutshwa namagesi angasebenzi njenge-ikhabhoni dayoksayidingesilinganiso esingu-1:9 ukuze kwakheke ingxube engaqhumi, ephephile kakhulu ekubulaweni nasekubulaweni amagciwane.I-ethylene oxideingapholimitha, kodwa ngokuvamile ipholimitha ihamba kancane futhi ikakhulukazi yenzeka esimweni soketshezi. Ezingxubeni ze-ethylene oxide ne-carbon dioxide noma ama-hydrocarbon afakwe i-fluorinated, ipholimitha iyenzeka kancane futhi amapholimitha aqinile awakwazi ukuqhuma.

Isimiso Sokuhlanza I-Ethylene Oxide

1. I-Alkylation

Indlela yokusebenza kwe-i-ethylene oxideEkubulaleni ama-microorganism ahlukahlukene ikakhulukazi i-alkylation. Izindawo zesenzo yi-sulfhydryl (-SH), i-amino (-NH2), i-hydroxyl (-COOH) kanye ne-hydroxyl (-OH) kuma-molecule e-protein kanye ne-nucleic acid. I-ethylene oxide ingabangela la maqembu ukuthi abhekane nokusabela kwe-alkylation, okwenza la ma-macromolecule e-biological ama-microorganisms angasebenzi, ngaleyo ndlela abulale ama-microorganism.

2. Vimbela umsebenzi wama-enzyme ezinto eziphilayo

I-ethylene oxide ingavimbela umsebenzi wama-enzyme ahlukahlukene ezinto ezincane, njenge-phosphate dehydrogenase, i-cholinesterase kanye nezinye i-oxidases, okuvimbela ukuqedwa kwezinqubo ezijwayelekile ze-metabolic zezinto ezincane futhi okuholela ekufeni kwazo.

3. Umphumela wokubulala kuma-microorganisms

Kokubilii-ethylene oxideuketshezi kanye negesi kunemiphumela enamandla yokubulala amagciwane. Uma kuqhathaniswa, umphumela wokubulala amagciwane wegesi unamandla kakhulu, futhi igesi yayo ivame ukusetshenziswa ekubulaleni nasekubulaleni amagciwane.

I-ethylene oxide iyi-sterilant esebenza kahle kakhulu ene-wide-spectrum sterilant enomphumela oqinile wokubulala nokuvimbela imizimba yokusabalala kwamagciwane, ama-bacterial spores, isikhunta, kanye namagciwane. Lapho i-ethylene oxide ihlangana nama-microorganism, kodwa ama-microorganisms aqukethe amanzi anele, ukusabela phakathi kwe-ethylene oxide nama-microorganisms kuyindlela evamile yokusabela kokuqala. Umthamo ovimbela ama-microorganisms ahlanzekile akhuliswe, ijika lokusabela liwumugqa oqondile enanini le-semi-logarithmic.

Uhla lokusetshenziswa kokubulala inzalo kwe-ethylene oxide

I-ethylene oxideAyilimazi izinto ezihlanziwe futhi inokungena okunamandla. Izinto eziningi ezingafaneleki ukuhlanza inzalo ngezindlela ezijwayelekile zingahlanzwa futhi zihlanzwe nge-ethylene oxide. Ingasetshenziswa ekuhlanzweni kwemikhiqizo yensimbi, ama-endoscope, ama-dialyzer kanye namadivayisi ezokwelapha alahlwayo, ukuhlanza izimboni kanye nokuhlanza inzalo kwezindwangu ezahlukahlukene, imikhiqizo yepulasitiki, kanye nokuhlanza izinambuzane ezintweni ezindaweni eziwubhubhane lwezifo ezithelelanayo (njengezindwangu ze-fiber zamakhemikhali, isikhumba, iphepha, amadokhumenti, kanye nemidwebo kawoyela).

I-ethylene oxide ayilimazi izinto ezihlanziwe futhi inokungena okunamandla. Izinto eziningi ezingafaneleki ukuhlanza inzalo ngezindlela ezijwayelekile zingahlanzwa futhi zihlanzwe nge-ethylene oxide. Ingasetshenziswa ekuhlanzweni kwemikhiqizo yensimbi, ama-endoscope, ama-dialyzer kanye namadivayisi ezokwelapha alahlwayo, ukuhlanza izimboni kanye nokuhlanza inzalo kwezindwangu ezahlukahlukene, imikhiqizo yepulasitiki, kanye nokuhlanza izinambuzane ezintweni ezindaweni eziwubhubhane lwezifo ezithelelanayo (njengezindwangu ze-fiber zamakhemikhali, isikhumba, iphepha, amadokhumenti, kanye nemidwebo kawoyela).

Izici ezithinta umphumela wokubulala inzalo wei-ethylene oxide

Umphumela wokubulala amagciwane we-ethylene oxide uthintwa yizici eziningi. Ukuze kufezwe umphumela omuhle kakhulu wokubulala amagciwane, kuphela ngokulawula ngempumelelo izici ezahlukahlukene lapho ingadlala khona indima yayo engcono kakhulu ekubulaleni amagciwane futhi ifeze injongo yayo yokubulala amagciwane kanye nokubulala amagciwane. Izici eziyinhloko ezithinta umphumela wokubulala amagciwane yilezi: ukuhlushwa, izinga lokushisa, umswakama ohlobene, isikhathi sokusebenza, njll.